6.2.A1:  William Harvey’s discovery of the circulation of the blood with the heart acting as the pump (Oxford Biology Course Companion page 290).

• Outline William Harvey’s role in discovery of blood circulation.

6.2.NOS:  Theories are regarded as uncertain- William Harvey overturned theories developed by the ancient Greek philosopher Galen on movement of blood in the body (Oxford Biology Course Companion page 290).

• Outline Galen’s description of blood flow in the body.

• Describe how Harvey was able to disprove Galen’s theory.

Intro to circulation notes

Galen and Harvey slides

Meet William Harvey animation

6.2.U1:  Arteries convey blood at high pressure from the ventricles to the tissues of the body (Oxford Biology Course Companion page 291).

• State the function of arteries.

• Outline the role of elastic and muscle tissue in arteries.

• State the reason for toughness of artery walls.

6.2.U2:  Arteries have muscle cells and elastic fibers in their walls (Oxford Biology Course Companion page 291).

• Describe the structure and function of the three layers of artery wall tissue.

 6.2.S1:  Identification of the blood vessels as arteries, capillaries or veins from the structure of their walls (Oxford Biology Course Companion page 294).

• Compare the diameter, relative wall thickness, lumen diameter, number of wall layers, abundance of muscle and elastic fibers and presence of valves in arteries, capillaries and veins.

• Given a micrograph, identify a blood vessel as an artery, capillary or vein.

Artery structure and function part of vessels table

FYI - arteries of the human body slides

Artery model

Vasoconstriction and dilation notes 

Exercise flow chart with vessels

CFU Blood Vessels

6.2.U3:  The muscle and elastic fibers assist in maintaining blood pressure between pump cycles (Oxford Biology Course Companion page 292).

• Describe the mechanism used to maintain blood flow in arteries between heartbeats.

• Define systolic and diastolic blood pressure. 

• Define vasoconstriction and vasodilation.

D.4.S2:  Interpretation of systolic and diastolic blood pressure measurements (Oxford Biology Course Companion page 691).

• State the cause of systolic and diastolic pressure.

• Describe how sound is used to measure blood pressure.

Blood pressure notes

Blood pressure handwritten notes

Blood pressure analog and digital lab

Blood pressure data submission form

Blood pressure lab debrief

Data comparing sitting, standing, exercise and recovery 

A&B:  Heads up! The cardiovascular secrets of giraffes

6.2.U4:  Blood flows through tissues in capillaries. Capillaries have permeable walls that allow exchange of materials between cells in the tissue and the blood in the capillary (Oxford Biology Course Companion page 293).

• Describe the structure and function of capillaries.

• Describe the cause and effect of diffusion of blood plasma into and out of a capillary network.

 6.2.S1:  Identification of the blood vessels as arteries, capillaries or veins from the structure of their walls (Oxford Biology Course Companion page 294).

• Compare the diameter, relative wall thickness, lumen diameter, number of wall layers, abundance of muscle and elastic fibers and presence of valves in arteries, capillaries and veins.

• Given a micrograph, identify a blood vessel as an artery, capillary or vein.

Capillary structure and function part of vessels table

Capillaries slides

Capillaries handwritten notes

6.2.U5:  Veins collect blood at low pressure from the tissues of the body and return it to the atria of the heart (Oxford Biology Course Companion page 293).

• State the function of veins.

• Outline the roles of gravity and skeletal muscle pressure in maintaining flow of blood through a vein.

 6.2.U6:  Valves in veins and the heart ensure circulation of blood by preventing backflow (Oxford Biology Course Companion page 294).

• Outline the structure and function of a pocket valve.

 6.2.S1:  Identification of the blood vessels as arteries, capillaries or veins from the structure of their walls (Oxford Biology Course Companion page 294).

• Compare the diameter, relative wall thickness, lumen diameter, number of wall layers, abundance of muscle and elastic fibers and presence of valves in arteries, capillaries and veins.

• Given a micrograph, identify a blood vessel as an artery, capillary or vein.

Vein structure and function part of vessels table

Veins slides

Veins handwritten notes

Review Practice recognizing vessels 

Vessel histology lab

Optional video:  12 yo has a venous malformation in face causing a huge balloon like mass

Virtual arteries, capillaries and veins histology lab

6.3.A1:  Causes and consequences of blood clot formation in coronary arteries (Oxford Biology Course Companion page 304).

• State the function of the coronary arteries. 

• Define coronary thrombosis.

• List sources of arterial damage that increase the risk of coronary thrombosis.

• List factors that are correlated with an increased risk of coronary thrombosis and heart attack.

D.1.A5:  Cholesterol in blood as an indicator of the risk of coronary heart disease (Oxford Biology Course Companion page 669).

• Outline factors that indicate that dietary cholesterol may not be the exclusive cause of the correlation between blood plasma cholesterol levels and risk of coronary heart disease. 

D.4.A3:  Causes and consequences of hypertension and thrombosis (Oxford Biology Course Companion page 690).

• Describe the relationship between atherosclerosis and thrombosis.

• Describe the relationship between atherosclerosis and hypertension.

• List consequences of hypertension.

• Outline factors that are correlated with a greater incidence of thrombosis and hypertension.

D.1.U8:  Overweight individuals are more likely to suffer hypertension and type II diabetes (Oxford Biology Course Companion page 664).

• Define hypertension.

• Outline the reasons for the relationship between weight gain and hypertension.

Cardiovascular disease notes

CFU Cardiovascular diseases

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Review question slides

Final knowledge audit

Kahoot review